\begin{tabular}{llll}
Rank & Pair & Description & NN \\
\hline
\bfseries 1 & \bfseries D00283 & \bfseries Clozapine & 0.769 \\
\bfseries\indb{C,D}   & \bfseries hsa1814 & \bfseries DRD3: dopamine receptor D3 & 0.455 \\
\hline
\bfseries 2 & \bfseries D02358 & \bfseries Metoprolol & 0.750 \\
\bfseries\indb{C,D}   & \bfseries hsa154 & \bfseries ADRB2: beta-2 adrenergic receptor & 0.434 \\
\hline
 3 &  D00604 &  Clonidine hydrochloride & 0.933 \\
   &  hsa147 &  ADRA1B: alpha-1B adrenergic receptor & 0.435 \\
\hline
 4 &  D03966 &  Eglumegad & 0.036 \\
   &  hsa2914 &  GRM4: glutamate receptor, metabotropic 4 & 0.768 \\
\hline
 5 &  D00255 &  Carvedilol & 0.380 \\
   &  hsa152 &  ADRA2C: alpha-2C adrenergic receptor & 0.489 \\
\hline
\bfseries 6 & \bfseries D04625 & \bfseries Isoetharine & 0.737 \\
\bfseries\indb{K}   & \bfseries hsa154 & \bfseries ADRB2: beta-2 adrenergic receptor & 0.434 \\
\hline
 7 &  D03966 &  Eglumegad & 0.036 \\
   &  hsa2917 &  GRM7: glutamate receptor, metabotropic 7 & 0.758 \\
\hline
\bfseries 8 & \bfseries D02340 & \bfseries Loxapine & 0.769 \\
\bfseries\indb{D}   & \bfseries hsa1812 & \bfseries DRD1: dopamine receptor D1 & 0.205 \\
\hline
 9 &  D00503 &  Perphenazine & 0.857 \\
   &  hsa1816 &  DRD5: dopamine receptor D5 & 0.529 \\
\hline
 10 &  D00682 &  Carboprost tromethamine & 0.914 \\
   &  hsa5739 &  PTGIR: prostaglandin I2 receptor (IP) & 0.150 \\
\hline
 11 &  D01973 &  Eletriptan hydrobromide & 0.417 \\
   &  hsa3361 &  HTR5A: 5-hydroxytryptamine&\\
     && (serotonin) receptor 5A & 0.304 \\
\hline
\bfseries 12 & \bfseries D00790 & \bfseries Chlorprothixene & 0.826 \\
\bfseries\indb{D}   & \bfseries hsa1814 & \bfseries DRD3: dopamine receptor D3 & 0.455 \\
\hline
 13 &  D00503 &  Perphenazine & 0.857 \\
   &  hsa3356 &  HTR2A: 5-hydroxytryptamine&\\
     && (serotonin) receptor 2A & 0.186 \\
\hline
\bfseries 14 & \bfseries D00079 & \bfseries Dinoprostone & 0.852 \\
\bfseries\indb{C,D}   & \bfseries hsa5731 & \bfseries PTGER1: prostaglandin E receptor 1&\\
     &&\bfseries (subtype EP1), 42kDa & 0.150 \\
\hline
 15 &  D02884 &  Ambuphylline & 0.650 \\
   &  hsa140 &  ADORA3: adenosine A3 receptor & 0.477 \\
\hline
\bfseries 16 & \bfseries D02250 & \bfseries Octreotide acetate & 0.759 \\
\bfseries\indb{K}   & \bfseries hsa6751 & \bfseries SSTR1: somatostatin receptor 1 & 0.456 \\
\hline
 17 &  D02354 &  Thiethylperazine & 0.793 \\
   &  hsa1814 &  DRD3: dopamine receptor D3 & 0.455 \\
\hline
\bfseries 18 & \bfseries D05113 & \bfseries Naltrexone & 0.714 \\
\bfseries\indb{C,D}   & \bfseries hsa4986 & \bfseries OPRK1: opioid receptor, kappa 1 & 0.563 \\
\hline
 19 &  D01712 &  Theophylline sodium acetate & 0.684 \\
   &  hsa140 &  ADORA3: adenosine A3 receptor & 0.477 \\
\hline
\bfseries 20 & \bfseries D00095 & \bfseries Epinephrine & 0.929 \\
\bfseries\indb{C,K}   & \bfseries hsa155 & \bfseries ADRB3: beta-3 adrenergic receptor & 0.423 \\
\hline
 21 &  D02614 &  Denopamine & 0.692 \\
   &  hsa154 &  ADRB2: beta-2 adrenergic receptor & 0.434 \\
\hline
 22 &  D02354 &  Thiethylperazine & 0.742 \\
   &  hsa148 &  ADRA1A: alpha-1A adrenergic receptor & 0.235 \\
\hline
\bfseries 23 & \bfseries D02147 & \bfseries Albuterol & 0.650 \\
\bfseries\indb{C,D}   & \bfseries hsa153 & \bfseries ADRB1: beta-1 adrenergic receptor & 0.434 \\
\hline
\bfseries 24 & \bfseries D00397 & \bfseries Tropicamide & 0.419 \\
\bfseries\indb{D,K}   & \bfseries hsa1131 & \bfseries CHRM3: cholinergic receptor, muscarinic 3 & 0.454 \\
\hline
\bfseries 25 & \bfseries D00283 & \bfseries Clozapine & 0.613 \\
\bfseries\indb{C,D}   & \bfseries hsa1132 & \bfseries CHRM4: cholinergic receptor, muscarinic 4 & 0.559 \\
\hline
\bfseries 26 & \bfseries D00442 & \bfseries Octreotide & 0.759 \\
\bfseries\indb{C,D,K}   & \bfseries hsa6755 & \bfseries SSTR5: somatostatin receptor 5 & 0.531 \\
\hline
\bfseries 27 & \bfseries D04375 & \bfseries Guanabenz & 0.667 \\
\bfseries\indb{K}   & \bfseries hsa151 & \bfseries ADRA2B: alpha-2B adrenergic receptor & 0.465 \\
\hline
\bfseries 28 & \bfseries D00397 & \bfseries Tropicamide & 0.414 \\
\bfseries\indb{K}   & \bfseries hsa1133 & \bfseries CHRM5: cholinergic receptor, muscarinic 5 & 0.471 \\
\hline
\bfseries 29 & \bfseries D00283 & \bfseries Clozapine & 0.405 \\
\bfseries\indb{C,D}   & \bfseries hsa152 & \bfseries ADRA2C: alpha-2C adrenergic receptor & 0.489 \\
\hline
 30 &  D00604 &  Clonidine hydrochloride & 0.933 \\
   &  hsa148 &  ADRA1A: alpha-1A adrenergic receptor & 0.421 \\
\hline
\bfseries 31 & \bfseries D00514 & \bfseries Dexmedetomidine & 0.385 \\
\bfseries\indb{K}   & \bfseries hsa151 & \bfseries ADRA2B: alpha-2B adrenergic receptor & 0.465 \\
\hline
 32 &  D00513 &  Pindolol & 0.243 \\
   &  hsa3363 &  HTR7: 5-hydroxytryptamine&\\
     && (serotonin) receptor 7 (adenylate cyclase-coupled) & 0.275 \\
\hline
\bfseries 33 & \bfseries D00283 & \bfseries Clozapine & 0.613 \\
\bfseries\indb{C,D}   & \bfseries hsa1131 & \bfseries CHRM3: cholinergic receptor, muscarinic 3 & 0.454 \\
\hline
 34 &  D00437 &  Nifedipine & 0.219 \\
   &  hsa152 &  ADRA2C: alpha-2C adrenergic receptor & 0.489 \\
\hline
\bfseries 35 & \bfseries D00371 & \bfseries Theophylline & 0.800 \\
\bfseries\indb{C,D,K}   & \bfseries hsa135 & \bfseries ADORA2A: adenosine A2a receptor & 0.514 \\
\hline
\bfseries 36 & \bfseries D00442 & \bfseries Octreotide & 0.759 \\
\bfseries\indb{C,K}   & \bfseries hsa6753 & \bfseries SSTR3 & 0.458 \\
\hline
\bfseries 37 & \bfseries D02356 & \bfseries Verapamil & 0.286 \\
\bfseries\indb{C}   & \bfseries hsa152 & \bfseries ADRA2C: alpha-2C adrenergic receptor & 0.489 \\
\hline
\bfseries 38 & \bfseries D00283 & \bfseries Clozapine & 0.467 \\
\bfseries\indb{C}   & \bfseries hsa11255 & \bfseries HRH3: histamine receptor H3 & 0.319 \\
\hline
 39 &  D00790 &  Chlorprothixene & 0.826 \\
   &  hsa1816 &  DRD5: dopamine receptor D5 & 0.529 \\
\hline
 40 &  D01352 &  Dinoprost tromethamine & 0.914 \\
   &  hsa5731 &  PTGER1: prostaglandin E receptor 1&\\
     && (subtype EP1), 42kDa & 0.294 \\
\hline
\bfseries 41 & \bfseries D02349 & \bfseries Dipivefrin & 0.393 \\
\bfseries\indb{K}   & \bfseries hsa151 & \bfseries ADRA2B: alpha-2B adrenergic receptor & 0.465 \\
\hline
\bfseries 42 & \bfseries D00136 & \bfseries Haloperidol & 0.375 \\
\bfseries\indb{C}   & \bfseries hsa152 & \bfseries ADRA2C: alpha-2C adrenergic receptor & 0.489 \\
\hline
\bfseries 43 & \bfseries D00454 & \bfseries Olanzapine & 0.417 \\
\bfseries\indb{C,D}   & \bfseries hsa152 & \bfseries ADRA2C: alpha-2C adrenergic receptor & 0.489 \\
\hline
\bfseries 44 & \bfseries D00715 & \bfseries Hyoscine methobromide & 0.704 \\
\bfseries\indb{D,K}   & \bfseries hsa1129 & \bfseries CHRM2: cholinergic receptor, muscarinic 2 & 0.423 \\
\hline
 45 &  D00676 &  Sumatriptan succinate & 0.714 \\
   &  hsa3354 &  HTR1E: 5-hydroxytryptamine&\\
     && (serotonin) receptor 1E & 0.551 \\
\hline
 46 &  D02354 &  Thiethylperazine & 0.793 \\
   &  hsa1816 &  DRD5: dopamine receptor D5 & 0.529 \\
\hline
 47 &  D02359 &  Ritodrine & 0.792 \\
   &  hsa153 &  ADRB1: beta-1 adrenergic receptor & 0.434 \\
\hline
\bfseries 48 & \bfseries D00283 & \bfseries Clozapine & 0.613 \\
\bfseries\indb{C,D}   & \bfseries hsa1133 & \bfseries CHRM5: cholinergic receptor, muscarinic 5 & 0.471 \\
\hline
\bfseries 49 & \bfseries D01712 & \bfseries Theophylline sodium acetate & 0.722 \\
\bfseries\indb{D}   & \bfseries hsa136 & \bfseries ADORA2B: adenosine A2b receptor & 0.514 \\
\hline
 50 &  D00513 &  Pindolol & 0.391 \\
   &  hsa152 &  ADRA2C: alpha-2C adrenergic receptor & 0.489 \\
\hline
\end{tabular}
