\begin{tabular}{llll}
Rank & Pair & Description & NN \\
\hline
\bfseries 1 & \bfseries D00574 & \bfseries Aminoglutethimide & 0.296 \\
\bfseries\indb{C}   & \bfseries hsa1589 & \bfseries CYP21A2: cytochrome P450,&\\
     &&\bfseries family 21, subfamily A, polypeptide 2 (EC:1.14.99.10) & 0.255 \\
\hline
\bfseries 2 & \bfseries D00542 & \bfseries Halothane & 0.667 \\
\bfseries\indb{D}   & \bfseries hsa1571 & \bfseries CYP2E1: cytochrome P450, family 2,&\\
     &&\bfseries subfamily E, polypeptide 1 (EC:1.14.14.1) & 0.607 \\
\hline
\bfseries 3 & \bfseries D00139 & \bfseries Methoxsalen & 0.310 \\
\bfseries\indb{D}   & \bfseries hsa1543 & \bfseries CYP1A1: cytochrome P450, family 1,&\\
     &&\bfseries subfamily A, polypeptide 1 (EC:1.14.14.1) & 0.735 \\
\hline
 4 &  D00437 &  Nifedipine & 0.237 \\
   &  hsa1585 &  CYP11B2: cytochrome P450,&\\
     && family 11, subfamily B, polypeptide 2 (EC:1.14.15.4 1.14.15.5) & 0.930 \\
\hline
\bfseries 5 & \bfseries D00437 & \bfseries Nifedipine & 0.237 \\
\bfseries\indb{D}   & \bfseries hsa1559 & \bfseries CYP2C9: cytochrome P450, family 2,&\\
     &&\bfseries subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) & 0.924 \\
\hline
 6 &  D00528 &  Caffeine & 0.250 \\
   &  hsa1549 &  CYP2A7: cytochrome P450, family 2,&\\
     && subfamily A, polypeptide 7 (EC:1.14.14.1) & 0.944 \\
\hline
 7 &  D00691 &  Dyphylline & 0.684 \\
   &  hsa5152 &  PDE9A: phosphodiesterase 9A (EC:3.1.4.35) & 0.171 \\
\hline
 8 &  D00410 &  Metyrapone & 0.345 \\
   &  hsa1583 &  CYP11A1: cytochrome P450,&\\
     && family 11, subfamily A, polypeptide 1 (EC:1.14.15.6) & 0.335 \\
\hline
 9 &  D03670 &  Deferoxamine & 0.140 \\
   &  hsa1579 &  CYP4A11: cytochrome P450,&\\
     && family 4, subfamily A, polypeptide 11 (EC:1.14.15.3) & 0.947 \\
\hline
 10 &  D00691 &  Dyphylline & 0.684 \\
   &  hsa8654 &  PDE5A: phosphodiesterase 5A,&\\
     && cGMP-specific (EC:3.1.4.35) & 0.217 \\
\hline
 11 &  D00126 &  Ibuprofen & 0.524 \\
   &  hsa247 &  ALOX15B: arachidonate 15-lipoxygenase,&\\
     && type B (EC:1.13.11.33) & 0.468 \\
\hline
 12 &  D00410 &  Metyrapone & 0.345 \\
   &  hsa1543 &  CYP1A1: cytochrome P450, family 1,&\\
     && subfamily A, polypeptide 1 (EC:1.14.14.1) & 0.735 \\
\hline
\bfseries 13 & \bfseries D00449 & \bfseries Sulfinpyrazone & 0.677 \\
\bfseries\indb{C}   & \bfseries hsa5742 & \bfseries PTGS1: prostaglandin-endoperoxide&\\
     &&\bfseries synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) & 0.640 \\
\hline
\bfseries 14 & \bfseries D05458 & \bfseries Phentermine & 0.562 \\
\bfseries\indb{D}   & \bfseries hsa4128 & \bfseries MAOA & 0.748 \\
\hline
\bfseries 15 & \bfseries D00947 & \bfseries Linezolid & 0.500 \\
\bfseries\indb{C}   & \bfseries hsa4129 & \bfseries MAOB: monoamine oxidase B (EC:1.4.3.4) & 0.748 \\
\hline
\bfseries 16 & \bfseries D00410 & \bfseries Metyrapone & 0.345 \\
\bfseries\indb{D}   & \bfseries hsa1585 & \bfseries CYP11B2: cytochrome P450,&\\
     &&\bfseries family 11, subfamily B, polypeptide 2 (EC:1.14.15.4 1.14.15.5) & 0.930 \\
\hline
 17 &  D00126 &  Ibuprofen & 0.524 \\
   &  hsa246 &  ALOX15: arachidonate 15-lipoxygenase&\\
     && (EC:1.13.11.33) & 0.668 \\
\hline
\bfseries 18 & \bfseries D00691 & \bfseries Dyphylline & 0.632 \\
\bfseries\indb{D}   & \bfseries hsa5150 & \bfseries PDE7A: phosphodiesterase 7A (EC:3.1.4.17) & 0.600 \\
\hline
\bfseries 19 & \bfseries D00537 & \bfseries Topiramate & 0.265 \\
\bfseries\indb{C}   & \bfseries hsa759 & \bfseries CA1: carbonic anhydrase I (EC:4.2.1.1) & 0.602 \\
\hline
\bfseries 20 & \bfseries D00097 & \bfseries Salicylic acid & 0.750 \\
\bfseries\indb{D}   & \bfseries hsa5743 & \bfseries PTGS2: prostaglandin-endoperoxide&\\
     &&\bfseries synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) & 0.640 \\
\hline
\end{tabular}
